How Methionine May Serve As A Natural Anti-depressant

Methionine is one of the 10 essential amino acids which cannot be manufactured in the body, and must therefore be obtained from the diet. Like other amino acids, methionine is vital for the formation of the countless proteins which make up not only the body's dry tissue, but many of its vital enzymes. Logically enough, as it is an essential component of protein, it is protein foods which are the best source of dietary methionine. Meat, poultry, fish and dairy products are known as first class proteins because they contain all of the essential amino acids. A diet containing a good supply of each of these food groups should normally provide sufficient amino acids, including methionine, for most purposes, but vegetarians can also achieve satisfactory intakes through careful food combining.

Particular attention, however, has been focussed on methionine as the precursor of s-adenosyl methionine, also known as SAM or SAM-e, a compound produced naturally in the body by the metabolism of methionine. S-adenosyl methionine was isolated in Europe in the 1950s, and has been used there as a prescription drug, but it has only very recently been seen as a food supplement in the US. A large number of biochemical reactions are known to require its presence, including the transmission of nerve impulses between cells. Conventional medical opinion insists that healthy people should obtain all the SAM-e they need for these purposes from their intake of dietary methionine, but various clinical or sub-clinical conditions may affect the body's ability to metabolize SAM-e in this way.

In particular, the brains of sufferers from depression have been observed to be deficient in s-adenosyl methionine as well as serotonin, the so-called "feel-good" hormone. There is some good research evidence from Europe that supplementation with between 800 and 1,600 mg per day of SAM-e increased serotonin levels, significantly improved the condition of patients suffering from moderately severe clinical depression, and was also helpful in some more severe cases. This research appears to validate the long standing practice of methionine supplementation by psychiatrists interested in the possibilities of nutritional therapy.

So there appear to be encouraging grounds for believing that methionine or SAM-e may be useful alternatives to conventional drug therapies in some cases of depression, and may offer similar benefits without the side effects of drugs.

But depression is only one of the conditions for which s-adenosyl methionine appears to offer therapeutic value. There's also good evidence from European studies that supplement doses similar to those used to tackle depression may be useful in tackling problems with liver function, including hepatitis and even cirrhosis. And given SAM-e's apparent potential for boosting emotional and psychological health, it has been suggested by some therapists that it may be useful in the rehabilitation programs of alcoholics and drug addicts.

At least one large scale study has shown the anti-inflammatory effects of s-adenosyl methionine to provide to relief from the symptoms of osteo-arthritis, and there are some more speculative grounds for believing that it may also be of benefit to sufferers from Parkinson's disease and multiple sclerosis.

Orthodox medical opinion, however, insists that more research is required before the potential value of s-adenosyl methionine for any of the above conditions can be definitively established. While these concerns may appear to reflect undue caution, it is certainly true in any case that supplements of methionine or any other amino acid should not be taken in isolation for any extended period of time because of the risk of creating an imbalance.

And importantly, in the case of s-adenosyl methionine, it needs to be noted that there is a potential risk of supplementation leading to a build up of homocysteine. This is another amino acid produced naturally in the body, but excess levels of which are known to be a factor in increasing the risk of cardiovascular and related diseases. Fortunately, however, this is a risk which may be easily avoided simply by ensuring a generous intake of the B vitamins, folic acid, B6 and B12. And, as always with the B complex, these do not function correctly in isolation, so that a good dietary supply of the entire complex is also required.

With this important caveat, and although its potential benefits have perhaps been exaggerated in the media, it does appear that supplementation with s-adenosyl methionine may be worth trying for sufferers of the specific conditions highlighted above, whose natural levels of methionine and SAM-e are likely to have been depressed both by their condition itself and other factors.

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About Steve P Smith

Steve Smith is a freelance copywriter specializing in direct marketing and with a particular interest in health products. Find out more at http://www.sisyphuspublicationsonline.com/LiquidNutrition/Methionine.htm


And here is another random article you might be interested in...

Bad Credit Repair

Building your credit after repeated interruptions is a constant headache we all want to avoid. In this article I am going to break it on down for you, since there are many sources that will take full advantage of you when the opportunity arise. If you feel bad simply because you can't meet your bills expectations at the moment they arrive, then you are not alone.

The fact is, even the best of us are struggling to meet some expectation that the system has placed on us. We calculate weekly the amount we spend on groceries, which are constantly increasing, as well as other bills that are constantly on the rise. It seems at times it is a no win situation, but the fact is there is always a solution to most problems.

The problem most times is some of us do not have the means to find those solutions. This brings forth more stress and often we feel that we are alone. If you trying to build your credit status you need to find the resources that can help you get results. The marketplace offers credit repair kits, which can lead us in the right direction to repairing credit, but the disadvantage is that many of the kits are expensive.

Let's face it, not everyone has the money to spend on commodities that claim to help us. Some of us struggle harder than others just to survive. Life is forever changing and in order to keep up with the changes we all have to find a solution. Therefore, I am going to tell you where you can get a free credit repair kit.

Your local library stores a wealth of information and it is free to the public. In most libraries that have credit repair kits, credit repair books, or debt management solution books. Anything you want at your disposal and it is all free information. The library also has copy and fax machines often, and if you notice in the credit repair guide or kit, it will have copies of the letters you can write to your creditors.

Make yourself some copies and once you fill them out as instructed, you are on your way to repairing your credit. The library also has guides or kits for filing bankruptcy. If you do not see a way out, then you may want to go this route. In most cases, you can do a Pro Bono Bankruptcy, which means you will represent yourself in the courtroom.

I just wanted to let you know that if you file a Chapter 7 Bankruptcy, you will have monthly installments to make, but if you file Chapter 13 Bankruptcy then the courts wipe out all your debts. The problem is that bankruptcies remain on credit files for up to ten years or longer. If you can avoid bankruptcy do so, however it is not the end of the world if you do.

I know people personally that filed bankruptcy and was able to get loans for mortgage, cars and so on. If you know what you are, doing you can do anything no matter how bad your situation is. Avoid Debt Consolidation, simply because it is means you will be paying fees and costs to others to get out of debt, which only adds up the bills.

You might want to consider a Debt Counselor from a respected organization. It makes sense to check out any business first before spending money or asking for services. The BBB offers free information on organizations, businesses and corporations. Once you have investigated the service then you will know if the people are really trying to help you.

Any service that tells you they can get you out of debt in no time at all is pulling your leg. The fact is even when you pay your bills your credit will continue to list all the bad debts, it will only say after the debt listed...Resolved. Finally message while I am thinking about it. It is important to get copies of your credit reports from TransUnion, Equifax, and Experian.

You can find any information you need online. Knowing your status in life is the beginning of repairing bad credit.

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About Jonathan Cheong

Jonathan Cheong

Discover the latest comprehensive resources for credit, loans and debt solutions. Click here => http://www.credit-loan-debt-solutions.com